Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic health. Obesity is a global epidemic and a risk factor for many diseases, including diabetes and cancer. Current obesity drugs require injections and can cause side effects, so a safe way to boost weight loss could deliver significant public health benefits. The study, led by Associate Professor Tristan Rawling from the University of Technology Sydney (UTS), has just been published ...

Researchers at Osaka Metropolitan University have discovered a practical way to detect and fix common labeling errors in large radiographic collections. By automatically verifying body-part, projection, and rotation tags, their research improves deep-learning models used for routine clinical tasks and research projects. Deep-learning models using chest radiography have made remarkable progress in recent years, evolving to accomplish tasks that are challenging for humans such as estimating cardiac and respiratory function. However, AIs are only as good as the images ...

Even a low daily intake of alcohol—-just 9 g or around one standard drink—is linked to a 50% heightened risk of mouth (buccal mucosa) cancer in India, with the greatest risk associated with locally brewed alcohol, finds a large comparative study, published online in the open access journal BMJ Global Health.   And when combined with chewing tobacco, it likely accounts for 62% of all such cases in India, the findings suggest.   Mouth cancer is the second most common malignancy in India, with an estimated 143,759 new cases and 79,979 deaths every year. Rates ...

Members of the American Meteorological Society (AMS), the professional society for weather, water, and climate sciences and services, have elected Richard (Rick) Spinrad to the position of AMS president-elect for 2026, as well as electing five new council members.  Spinrad, an oceanographer, formerly served as U.S. Under Secretary of Commerce for Oceans and Atmosphere and the 11th administrator of the National Oceanic and Atmospheric Administration (NOAA). He will be inducted as president-elect on Sunday, 25 January, 2026, during the AMS’s 106th Annual Meeting in Houston, Texas.  The five newly elected AMS Council Members are Marilyn Averill, Julie Demuth, Jordan Gerth, ...

As countries around the world grapple with the challenge of achieving net-zero emissions, a newly released online webinar recording is drawing attention to one of the most promising and underappreciated climate solutions: biomass-based carbon capture. The full recording of the international seminar, held online on December 17, 2025, is now freely available on YouTube, offering researchers, policymakers, and the public an accessible deep dive into how nature’s carbon cycle can be harnessed for large-scale climate mitigation. The webinar, ...

  Invisible pollutants at the nanoscale are quietly entering bodies and ecosystems, yet standard toxicology tools still treat living organisms like a black box. A new perspective article in the journal New Contaminants describes how cutting edge bioimaging is turning that black box into a transparent map, revealing where these particles go and how they may harm health. Lighting up hidden nano pollution Emerging nanoscale contaminants such as engineered nanomaterials and nanoplastics are now found in water, soil, food and even the air we breathe, but their tiny size and complex behavior make them hard to track with traditional methods. Conventional ...

EMBARGOED FOR RELEASE UNTIL 4:00 P.M. ET, TUESDAY, DECEMBER 23, 2025 MINNEAPOLIS — A new study published on December 23, 2025, in Neurology®, the medical journal of the American Academy of Neurology, looks at how age may affect recovery for people with spinal cord injuries. “With population growth and improvements in medicine, the number of people diagnosed with spinal cord injury is increasing and the average age at the time of injury is rising,” said study author Chiara Pavese, MD, PhD, of the University of Pavia in Pavia, ...

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient’s oropharyngeal cancer—a type of head and neck cancer that develops in the throat—will spread, thereby signaling which patients should receive aggressive treatment. The research is published in Journal of Clinical Oncology. “Our tool may help identify which patients should receive multiple interventions or would be ideal candidates for clinical trials of intensive strategies such ...

RIVERSIDE, Calif. -- A study led by biomedical scientists at the University of California, Riverside, has shown for the first time that a father’s exposure to microplastics (MPs) can trigger metabolic dysfunctions in his offspring. The research, conducted using mouse models, highlights a previously unknown pathway through which environmental pollutants impact the health of future generations. While MPs have already been detected in human reproductive systems, the study, published in the Journal of the Endocrine Society, is the first to bridge the gap between paternal ...

“The insights gained from this study not only validate OVCAR3 as a representative model for HGSOC, but also provide a foundation for developing targeted therapeutic strategies.” BUFFALO, NY — December 23, 2025 — A new research paper was published in Volume 12 of Oncoscience on October 14, 2025, titled “Bridging clinical insight and laboratory model in high-grade serous ovarian carcinoma (HGSOC) using DNA sequencing-based profiling of TP53.” In this study, Faisal Iqbal from the University ...

FAIRFAX, VA (Dec. 23, 2025)—Registration is open for the Society of Interventional Radiology (SIR) 2026 Annual Scientific Meeting. Join top interventional radiologists to shape the future of the specialty, April 11–15, 2026, at the Metro Toronto Convention Centre in Toronto, Ontario, Canada. More than just a conference, SIR’s Annual Scientific Meeting is a gathering place for a vibrant, inclusive community of more than 4,000 IR professionals—from those in training to seasoned experts. The scientific program ...

The International Society for Stem Cell Research (ISSCR) today announced the 10 most downloaded papers of 2025 from Stem Cell Reports, its peer-reviewed, open-access journal. Together, these highly read articles reflect the extraordinary scientific range of the field – from foundational mechanisms of pluripotency and differentiation to translational advances in regenerative medicine, disease modeling, and bioethics – and underscore the journal’s role as a trusted platform for impactful stem cell science. Engineered Proxies and the Illusion of De-Extinction A timely and widely discussed perspective examining recent claims of “de-extinction,” using dire ...

FOR IMMEDIATE RELEASE Oxford-led study estimates NHS spends around 3% of its primary and secondary care budget on the health impacts of heat and cold in England Analysis of 4.37 million patient records in England finds resources asymmetrically impacted by winter cold and summer heat, with about 64% linked to common cold days while very hot days drive sharp same-day demand surges A new University of Oxford-led study, published in The Lancet Planetary Health, is the first to link daily temperature data to health-care use and costs across primary and secondary care in England. Using ...

Since his postdoctoral days at MIT, Hang Yu, associate professor of materials science and engineering, has been wrestling with the challenge of creating a shape-memory ceramic that can be manufactured at scale without breaking. Now, in tandem with Ph.D. student Donnie Erb '15, M.S. '18 and postdoctoral researcher Nikhil Gotawala, he’s had a breakthrough. Yu’s team has used an advanced manufacturing technique called additive friction stir deposition to embed functional ceramic particles into metal. The result? A strong, defect-free material that can phase-shift under stress to dissipate energy and, unlike normally brittle ceramics, can be 3D-printed in ...

As cities grow and natural habitats shrink, urban wildlife must adapt to rapidly changing environments. A new study published in Insect Science shows that the guts of urban-dwelling wild bees contain detailed microbial signatures that reflect both bee health and the quality of the surrounding environment, offering a powerful new tool for monitoring ecological well-being in cities. Researchers at Xi’an Jiaotong-Liverpool University (XJTLU) used metagenomic sequencing of the solitary mason bee Osmia excavata to analyze dietary pollen, gut bacteria and viruses, ...

Older adults who live in economically disadvantaged neighborhoods spend significantly fewer days at home in the year after a fall-related hip fracture than those living in more affluent areas, according to a large national study published today in JAMA Network Open. The study analyzed Medicare data from more than 52,000 older adults who experienced a hip fracture. Researchers found that people living in the most disadvantaged neighborhoods spent about 23 fewer days at home during the year after their injury compared with those in the least disadvantaged areas after considering individual factors such as age or chronic illnesses.  “Neighborhood ...

About The Study: Commercial autonomous vehicle (AV) availability and adoption are underway and could impact national road traffic injuries. In this simulation study, potential injury reductions in the U.S. were forecasted using several scenarios based on real-world data. The results of this study suggest that AV adoption may reduce expected injuries; however, predicted confidence intervals remain broad for the baseline injury forecast, and none of the scenarios reduced expected injuries outside of these bounds.  Corresponding Author: To contact the corresponding author, Avery B. Nathens, MD, MPH, PhD, email avery.nathens@sunnybrook.ca. To access the embargoed study: Visit our For The ...

About The Study: In this serial cross-sectional study of nationally representative administrative data from 2016 to 2022, the rate of alcohol-related hospitalizations was stable while mortality, length of stay, and health care costs all increased. Preventive efforts are needed to improve outcomes and reduce health care spending by reducing population-level alcohol consumption and engaging patients in alcohol use disorder treatment before progression to alcohol-related hospitalizations. Corresponding Author: To contact the corresponding author, Eden Y. Bernstein, MD, MPH, email eden.bernstein@cuanschutz.edu. To access the embargoed ...

About The Study: In this prespecified exploratory analysis of the SELECT randomized clinical trial, the trial cohort had a high rate of hospital admissions. Treatment with once-weekly semaglutide was associated with significant reductions in hospital admissions and overall time spent in hospital, extending its benefits beyond cardiovascular risk reduction. Corresponding Author: To contact the corresponding author, Stephen J. Nicholls, MD, email stephen.nicholls@monash.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamacardio.2025.4824) Editor’s ...

Key points: A system which replicates the womb lining (endometrium) with high biological fidelity has been developed by researchers at the Babraham Institute and used to listen in to the communication that happens between the embryo and endometrium at the crucial stage of development when the embryo implants. Using donated endometrial tissue to seed the model, the approach provides the most advanced culture system for understanding how early-stage human embryos implant into the endometrium to establish ...

For many of us, the holiday season can mean delightful overeating, followed by recriminatory New Year’s resolutions. But eating enough and no more should be on the menu for all of us, according to a recent UBC study. It found that 44 per cent of us would need to change our diets for the world to warm no more than 2 C. Dr. Juan Diego Martinez, who led the research as a doctoral student at UBC’s Institute for Resources, Environment and Sustainability, discusses the study’s findings and the simple dietary changes we can all make. What did you find? Half of us globally and at least 90 per cent of Canadians need to ...

To answer this question: How to make AI truly scalable and reliable for real-time traffic assignment? A research team from KTH Royal Institute of Technology, Monash University, Technical University of Munich, Southeast University, and the University of Electro-Communications has developed a new framework—MARL-OD-DA—that offers a promising answer. The approach redesigns learning agents at the origin–destination (OD) level and utilizes Dirichlet-based continuous actions to achieve stable and high-quality solutions under dynamic travel demand.   The team published their ...

Ride-pooling is widely recognized as a sustainable way to ease congestion, reduce costs and cut emissions, yet adoption remains limited.  When operators act independently, efficiency is low because requests cannot be matched across platforms.  Aggregation platforms seek to improve this by forcing all operators into a permanent coalition, but differences in size, cost and market position make such arrangements unstable.  To address this, researchers from Beihang University and Delft University of Technology developed a multi-level coalition formation game framework that enables coalitions to form dynamically in response to trip requests, allowing flexible cooperation ...

Researchers at Tsinghua University developed PriorFusion, a unified framework that integrates semantic, geometric, and generative shape priors to significantly improve the accuracy and stability of road element perception in autonomous driving systems. The research addresses a long-standing challenge: existing end-to-end perception models often generate irregular shapes, fragmented boundaries, and incomplete road elements in complex urban scenarios.   The team published their study in Communications in Transportation Research on November 18, 2025.   “We design PriorFusion to introduce shape priors into every ...

“This study outlines shifting priorities and translational gaps in aging research and offers a scalable, data-driven alternative to conventional reviews.” BUFFALO, NY — December 23, 2025 — A new research paper was published in Volume 17, Issue 11 of Aging-US on November 25, 2025, titled “A natural language processing–driven map of the aging research landscape.” In this study, Jose Perez-Maletzki from Universidad Europea de Valencia and Universitat de València, together with Jorge Sanz-Ros from Stanford University ...