Research reporting case study
The COMPare project followed trial publications back to their plans. Use its findings to inspect an outcome change without jumping to accusations.
Research reporting case study
A historical audit of large trials shows why a literature search needs a results registry—and why an absent paper is not the same as an absent result.
Research methods
Learn to separate adverse events from adverse reactions, count people rather than episodes and interpret zero events without claiming zero risk.
Evidence reading guide
A combined outcome can tell a useful story while leaving its most important chapter unresolved. Work through a first-event example and learn what to look for in the component results.
Research methods
A worked guide to precision, clinical importance and the difference between an uncertain result and evidence of little effect.
Research methods
Use two fictional populations to see how sensitivity, specificity and the frequency of a condition shape what a positive result means.
Research methods
Follow a simple time-to-event model to see why hazard ratios, risks at a fixed time and survival duration answer different questions.
Evidence reading guide
A pooled estimate is the end of a chain of decisions. Trace the question, search, independent studies, bias and uncertainty before deciding what the headline deserves.
BEHIND THE HEADLINE A finding is only the beginning. Who was studied? How large was the effect? What remains uncertain?
Our research briefs begin with the publication, and keep the sources in view.
Inside our editorial process